Thermo Scientific™ High Select HSA/Immunoglobulin Depletion Resin decreases the albumin and antibody components that are abundant in human plasma samples, helping prepare the samples for mass spectrometry or 1D or 2D electrophoresis.
- Flexible: Provided in bulk format for depletion of user-defined amount of human plasma sample
- Optimised: Removes >95% of IgG and >95% of albumin
- Fast: Process samples in ~10 minutes
- Economical: Cost-effective bulk format
High Select HSA/Immunoglobulin Depletion Resin uses highly specific immobilised anti-HSA and anti-immunoglobulin antibodies (IgG, IgA, IgM, IgD, and IgE) to remove human serum albumin (HSA) and all major subclasses of immunoglobulins from serum or plasma. The resin is provided in an economical bulk format that may be used to fill columns or plates, depending on the sample volumes.
Analysis of human fluids is often complicated by the presence of high concentrations of albumin and IgG that can make up more than 70% of total serum protein. Removal of these proteins is often essential for the study of low-abundant proteins. High Select HSA/Immunoglobulin resin can deplete greater than 95% of HSA and 95% of IgG. Columns or plates are filled with resin based on the needs of the user, and samples are processed in approximately 10 minutes. The depletion of highly abundant proteins enables the detection of low abundant proteins in samples and subsequent identification by mass spectrometry or 1D or 2D gel electrophoresis.