2-Methoxyestradiol ELISA kit

Leverandør: Cayman Chemical
Ratings: Ingen bedømmelse

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CAYM582261-96EA 8280 DKK
CAYM582261-96 CAYM582261-480 CAYM582261-480S CAYM582261-96S
2-Methoxyestradiol ELISA kit
Assays ELISAs
A competitive assay that can be used for quantification of 2-methoxyestradiol in plasma, urine, and other sample matrices.

  • Detect 2-ME2
  • Assay 24 samples in triplicate or 36 samples in duplicate
  • Measure 2-ME2 levels down to 40 pg/ml
  • Colorimetric read at 405 to 420 nm

2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol produced by CYP450-dependant hydroxylation followed by catechol-O-methyltransferase-catalyzed O-methylation. Deficiency in catechol-O-methyltransferase is associated with pre-eclampsia. Therefore, 2-ME2 may be utilized as a plasma and urinary diagnostic marker for this disease, as well as a therapeutic supplement for its prevention. Several clinical trials have demonstrated the antitumor effects of 2-ME2 in prostate cancer, breast cancer, renal cell carcinoma, ovarian cancer, glioblastoma, and multiple myeloma. Other studies indicate that 2-ME2 exhibits more potent cardioprotective effects than estradiol. Cayman’s 2-Methoxyestradiol ELISA Kit is a competitive assay that can be used for quantification of 2-ME2 in plasma, urine, and other sample matrices.

Leveringsinformation: Kit contains antibody, tracer, standard, ELISA and wash buffer concentrate, polysorbate 20, plate and cover sheet, Ellman's reagent, tracer and antiserum dye.
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