The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.
BLM antibody can be used in ELISA starting at 1:5000 - 1:20000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation
Protein G Column
PBS, 0.1% sodium azide.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type:
Antigen: BLM
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human