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Anti-MST1R Rabbit Polyclonal Antibody

Leverandør: ProSci Inc.
MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers.

MST1R antibody can be used in immunohistochemistry starting at 20 μg/mL, and immunofluorescence.

PBS, 0.1% sodium azide.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type:
Antigen: MST1R
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Bat, Gorilla, Human, Monkey



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Størrelse Pakn VWR katalog nummer Mængde
50 µg 50 µG PRSI48-321
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Specifikationer

Antigen symbol MST1R
Antigen name Macrophage Stimulating 1 Receptor
Reactivity Bat, Monkey, Gorilla, Human
Conjugation Unconjugated
Clonality Polyclonal
Host Rabbit
ImmunoChemistry Yes
Antigen synonyms soluble RON variant 2, RON, RON variant E2E3, PTK8, CDw136, MST1R variant RON30, CD136, MST1R variant RON62, p185-Ron, soluble RON variant 1, PTK8 protein tyrosine kinase 8, soluble R, MSP receptor, soluble RON variant 3, c-met-related tyrosine kinase, macrophage-stimulating protein receptor
Immunogen MST1R antibody was raised against a peptide located near the internal domain of MST1R (Human).
Form Liquid
Tested Applications Immunoaffinity Chromatography

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