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Anti-GPR182 Rabbit Polyclonal Antibody

Leverandør: ProSci Inc.
G Protein-Coupled Receptor L1/G10D (GPR182) has been suggested to be an Adrenomedullin Receptor. Originally cloned from rats and later from humans, L1/G10D does not to bind adrenomedullin or display functional cAMP response to adrenomedullin . The initial experimental results, which demonstrated high-affinity binding and increased levels of cAMP in COS cells that were transfected with L1/G10D and treated with adrenomedullin, could not be reproduced by other laboratories (Kapas et al. 1995). It is now known that the functional adrenomedullin receptor is a heterodimeric complex composed of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) (McLatchie et al. 1998). L1/G10D therefore should be considered an Orphan A receptor.

GPR182 antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.

PBS, 0.1% sodium azide.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type:
Antigen: GPR182
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human



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Størrelse Pakn VWR katalog nummer Mængde
50 µg 50 µG PRSI48-233
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Specifikationer

Antigen symbol GPR182
Antigen name G Protein-coupled Receptor 182
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Host Rabbit
ELISA Yes
ImmunoChemistry Yes
Antigen synonyms G10D, AMR, AM-R, ADMR, hrhAMR, gamrh, 7TMR
Immunogen GPR182 antibody was raised against a peptide located in the C-Terminal domain of GPR182 (Human).
Form Liquid
Tested Applications Immunoaffinity Chromatography

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