The Mag-Bind® EquiPure Normalization Kits can be used to normalise and purify gDNA and DNA libraries from various DNA concentrations. Using Mag-Bind® normalizer beads and a binding buffer system, input DNA of various quantities is simply bound, washed and eluted to a final normalised product. The magnetic beads have a limited binding capacity and therefore allow a predefined amount of DNA to be captured and eluted.
- DNA output concentrations of ±10%
- No quantification required
- Normalises genomic DNA or NGS libraries
Many high-throughput applications, such as sequencing and genotyping, require the input DNA concentration to be within a certain range for optimal results. Traditionally, a tedious process of quantification, calculation and concentration adjustment must be carried out to normalise the DNA samples. The Mag-Bind® EquiPure Normalizer Kit completely eliminates the need to quantify and aliquot DNA, saving time, quantification bias and tip cost.
The Mag-Bind® EquiPure Normalizer Kits are fully automatable on multiple liquid handling platforms, including Hamilton STAR, Tecan Evo, Caliper Sciclone, and Beckman Coulter Biomek instruments.