Human Recombinant DKK1

Leverandør: Tonbo Biosciences
Ratings: Ingen bedømmelse

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21-7100-U100EA 6890 DKK
21-7100-U100 21-7100-U002 21-7100-U500 21-7100-U010
Human Recombinant DKK1
Proteiner
The DKK (Dickkopf) family of secreted proteins includes DKK-1 through -4, and a related protein, Soggy (DKK-11). DKK-1 is an antagonist of the Wnt signaling pathway, forming inhibitory complexes with Wnt co-receptors LRP5 or LRP6 along with Kremen-1 or Kremen-2. DKK-1 is expressed during development and, in the adult, is expressed in osteoblasts and osteocytes. Over- or under-expression of DKK-1 can result in decreased or increased bone density.
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