Anti-AGPAT6 Rabbit Polyclonal Antibody

Leverandør: Thermo Fisher Scientific
Ratings: Ingen bedømmelse

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PIEAPA116960EA 0 DKK
PIEAPA116960
Anti-AGPAT6 Rabbit Polyclonal Antibody
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This antibody is expected to react with bovine, porcine, and rat samples based on sequence homology. Suggested positive control: mouse skeletal muscle lysate or protein. AGPAT6 is a novel glycerolipid acyltransferase of the ER, which is crucial for the production of milk fat by the mammary gland. Agpat6 deficient mice exhibit a 25% reduction in body weight and resistance to both diet-induced and genetically induced obesity. The reduced body weight is associated with increased energy expenditure, reduced triglyceride accumulation in BAT and WAT, reduced white adipocyte size, and lack of adipose tissue in the subdermal region. AGPAT6 plays a unique role in determining triglyceride content and composition in adipose tissue and liver that cannot be compensated by other members of the Agpat family.

Type: Primary
Antigen: AGPAT6
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Primates, Mouse
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