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Anti-POU5F1 Rabbit Polyclonal Antibody

Leverandør: Thermo Scientific
This antibody is expected to react with swine, feline and bovine samples based on a 93% sequence homology. Stem cells are crucial ingredients in the progressive restriction of cellular developmental capacity during mammalian embryogenesis. Until recently, only embryonic stem cells (ESC) had been shown to exhibit the potential to differentiate into cells of the all three germ layers. However, adult stem cells (ASC) can regain pluripotency (potential to differentiate into various lineages) if transferred from one stem-cell microenvironment into another. The transcription factor OCT4, expressed in ESCs and germ cells, is strongly implicated in the process of maintaining as well as regaining stem-cell pluripotency and functions as a key regulator of mammalian germline development.

Type: Primary
Antigen: POU5F1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Primates, Rat, Mouse




 

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Specifikationer

Antigen symbol POU5F1
Antigen name POU Class 5 Homeobox 1
Reactivity Rat, Primates, Human, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ImmunoFluorescence Yes
Flow cytometry Yes
Antigen synonyms Octamer-binding transcription factor 3 antibody, OTF3 antibody., Oct-4, POU domain class 5 transcription factor 1 antibody, OCT3, Oct-3
Gene ID 18999, 294562, 5460
Koncentration 1 mg/ml
Immunogen Synthetic peptide between amino acids 100-200 of the human OCT4 protein.
Purification Antigen affinity chromatography
Form Liquid
Storage buffer tris glycine, 0.15M NaCl, 0.05% sodium azide
Opbevaringstemperatur -20° C, Avoid Freeze/Thaw Cycles
Shipping temperature Ice

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