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Anti-NOD2 Rabbit Polyclonal Antibody

Leverandør: Thermo Scientific
This antibody is predicted to react with monkey based on 100% sequence homology. NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn's disease.

Type: Primary
Antigen: NOD2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human



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Specifikationer

Antigen symbol NOD2
Antigen name Nucleotide binding oligomerization domain containing 2
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Antigen synonyms NOD-2, IBD1, NOD 2, CARD15, Caspase recruitment domain protein 15, Inflammatory Bowel disease protein 1
Gene ID 64127
Koncentration 0.87 mg/ml
Immunogen A synthetic peptide made to the C-terminal region of the human NOD2 protein sequence (between residues 1,000-1,040).
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer tris glycine, 150mM NaCl, 0.05% sodium azide
Opbevaringstemperatur Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice

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