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Anti-ABCG8 Rabbit Polyclonal Antibody

Leverandør: Thermo Scientific
Longer exposure times are needed to visualize the wild type ABCG8. ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.

Type: Primary
Antigen: ABCG8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse



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200 µL 200 µl PIEAPA116798 Blocked
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Specifikationer

Antigen symbol ABCG8
Antigen name ATP Binding Cassette, sub-family G, member 8
Reactivity Mouse, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoFluorescence Yes
Antigen synonyms MGC142217, GBD4, STSL
Gene ID 67470, 64241
Koncentration 1 mg/ml
Immunogen A synthetic peptide from the n-terminal region of human ABCG8 protein.
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer tris citrate, 0.02% sodium azide, pH 7-8
Opbevaringstemperatur -20° C, Avoid Freeze/Thaw Cycles
Shipping Temperature Ice

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