Anti-Presenilin 2 Rabbit Polyclonal Antibody

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BSBTPA1358EA 4110 DKK
BSBTPA1358
Anti-Presenilin 2 Rabbit Polyclonal Antibody
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Rabbit IgG polyclonal antibody for Presenilin-2(PSEN2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Presenilin-2 is a protein that in humans is encoded by the PSEN2 gene. Kovacs et al.(1996) demonstrated that the expression patterns of PS1 and PS2 in the brain are extremely similar to each other and that messages for both are primarily detectable in neuronal populations. Immunochemical analyses indicated that PS1 and PS2 are similar in size and localize to similar intracellular compartments(endoplasmic reticulum and Golgi complex). Li et al.(1997) demonstrated that wildtype PS1 and PS2 are localized to the nuclear membrane, its associated interphase kinetochores, and the centrosomes.In melanocytic cells PSEN2 gene expression may be regulated by MITF.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.

Type: Primary
Antigen: Presenilin 2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: near the N-terminus
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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