Update on HPLC Analysis of Polar Compounds

Thursday, 9th July, 2020 
1:00 pm CEST (Berlin, Paris, Madrid)


Small polar molecules, like glyphosate, acrylamide, amino acids and many others have always been difficult to analyze in traditional reversed phase LC. They generally show small or no retention and it is more complicated to separate them from the other components in the mix and from matrix interferences. Restek has recently designed 2 new and unique stationary phases to overcome these challenges and we will discuss features (HILIC separation mode, IEX separation mode, 100% aqueous) and advantages (reproducibility, sensitivity, direct injection, equilibration time, analysis time) of these 2 new phases for the analysis of a wide variety of acidic, basic and neutral polar compounds.